Preclinical Pain Models
Preclinical models of inflammatory and rheumatoid arthritis pain involve the injection of immunogenic or non-immunogenic adjuvants in the joints or in the systemic system.
Neuropathic pain models involve partial nerve injury such as ligature of the spinal or sciatic nerves.
At Aginko we provide the following pain models:
  • Post surgical pain models
  • Visceral pain
  • Acute and chemogenic pain
  • Inflammatory pain
  • Neuropathic pain
  • Bone and joint pain

Endpoints assessment of quality of lige in a preclinical model of arthritis:
  • Paw withdrawal test (latency and duration)
  • Static weight-bearing
  • Validted pain scores for several animal species
  • Video-monitoring of animals (behavioural studies)
  • Algometry
  • Electrophysiology

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AGINKO Research AG, Route de l'ancienne Papeterie 7
1723 Marly , Switzerland