Aginko
BIOANALYTICS
 

AGINKO has a medical diagnostic laboratory that offers a comprehensive range of laboratory services to its clients. Aginko has developed its laboratory in the past years to satisfy the clients' need and exceed expectations. 
 

Our in-house pathologist grades the histological slides with appropriate and project-specific grading scales. Reports integrate representative light microscopy pictures.

AGINKO provides Contract Histology Services to support pre-clinical and clinical histology of medical research studies in tissue from humans and other species.

  

We offer:

 

  • Tissue processing, embedding in paraffin and sectioning at different thickness, staining with standard and/or specific dyes.
  • Image analysis histomorphometry and reporting

 

 

We can undertake an extensive range of specialized staining methods to identify specific tissues, cell types and tissue/cell.

 

  

AGINKO has extensive experience in providing immunohistochemistry services to screen healthy and diseased tissues using an extensive range of antibodies directed against specific biomarkers or against cell signaling proteins.

 

 

We support Target Validation and Target Distribution Studies by demonstrating and quantifying the expression of a particular target within cells/tissues which can be used either as predictive or prognostic tissue biomarkers in tissues originating from preclinical animal models or from clinical trials.

 

 

We offer a complete panel of bone and cartilage turnover markers reflecting the process in formation and degradation of cartilage or bone. These markers are suitable for cells culture, in different animals species from rodents to mammals, and in blood or urine tests samples.

 

 

We have developed a special kit for clinical biopsy of cartilage repair procedures that permits to maintain tissue phenotype for further analysis.

 


Regular Staining



Hematoxylin & Eosin
Safranin O
Toluidine Blue
Masson Trichrome
Alcian Blue
Sirius red
Other upon request

 

   

    Safranin-O staining of Rat Articular Cartilage



Immunohistochemistry Staining

 
 


COLI
COLII
COLIII
Aggrecan
Osteocalcin
CRATC1
S100B
NRN1

 
   Collagen I staining of sheep trochlea                     Collagen II staining of sheep condyle
 


NRN1

  • LPL
  • Bone ALP

 

 

 
 
 
  
   Osteocalcin staining zoom of sheep trochlea      Bone ALP staining zoom of sheep condyle defect
 

We also have a cell-culture laboratory and are equipped to run cell based research assays.
Once the assay is developed and validated, 
then your samples can be analyzed.

 

AGINKO continuously develops its stocks and services to satisfy the clients' requests.

Copyright © 2018 All rights reserved
AGINKO Research AG
AGINKO Research AG, Route de l'ancienne Papeterie 7
1723 Marly , Switzerland