Histology and laboratory Services

Aginko Research operates a medical diagnostic laboratory that provides a wide range of in-house laboratory services to its clients.

Over the years, Aginko Research has expanded its laboratory to meet and exceed client expectations. We specialise in various staining techniques to identify specific tissues, cell types and cells.

Aginko Research is highly experienced in offering immunohistochemistry services, using a broad array of antibodies to screen both healthy and diseased tissues, targeting specific biomarkers or cell signalling proteins.

We support Target Validation and Target Distribution Studies by demonstrating and quantifying the expression of specific targets within cells or tissues, which can be used as predictive or prognostic biomarkers in tissues from preclinical animal models or clinical trials.

 

Histology Services

Fact 1  
The lack of pathologists on the market.
Aginko Research is proud to have an in-house pathologist with a wealth of experience in the examination and evaluation of tissue morphology and the high level of expertise in the field of histology, histopathology and immunohistochemistry.
 
Fact 2
Unique network and experience.
Concurrently, a unique niche network of experienced pathologists and scientific experts build along the years, allows Aginko Research to provide the best, most comprehensive and cost-effective support to its clients.
 
Fact 3
Automated and digitalised.
Aginko Research recognises the true value of automatisation and digital pathology and eliminates the issues associated with sharing slides such as the degradation of samples and inability to share samples of live cells. 
 
Fact 4
Full processing.
Our histopathology laboratory can support every stage of the tissue analysis process. Even with biomaterials that are “difficult” or “impossible” to process, our extensive knowledge of materials chemistry enables preservation of intact tissue/material interfaces and even recovery of data from poorly embedded specimens obtained from external histology laboratories.
 
Fact 5.
Stains matter. 

Aginko Research offers a wide variety of histological stains including routine to special stains.

Visit our art gallery at aginko-histology.com

 

Laboratory Analysis

Aginko Research can provide you with the following laboratory analyses:

  • Synovial fluid or blood (serum) protein ELISA (e.g. cytokines or metalloproteinases):
    • IL-1beta,
    • IL-6,
    • TNF-alpha,
    • MMP3,
    • MMP13, etc.

 

  • Serum biochemistry:
    • AST,
    • ALT,
    • BUN
    • Creatinine, etc.

 

  • qRT PCR of cartilage lysate:
    • IL-1beta,
    • IL-6,
    • TNF-alpha,
    • MMP-3,
    • MMP-13,
    • ADAMTS5,
    • collagen 1,
    • collagen 2, etc.

 

  • Bio-imaging techniques to evaluate bone resorption, formation, fracture and cartilage degeneration repair but also various other parameters: 
    • X-ray and Contact Radiography,
    • In vivo Computed Tomography,
    • Micro-Computed Tomography,
    • Magnetic Resonance Imaging (MRI),
    • In vivo Bioluminescence Imaging.

 

We can assist you with your custom analysis protocol testing and optimisation.
Please do not hesitate to inquire about other analyses tailored to your exact needs.
 

Osteoarticular and inflammation focused preclinical and clinical research organisation (CRO)

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Route de l'ancienne Papeterie 106
1723 Marly
Switzerland

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