Infection models
Bone and joint inflammatory diseases encompass infections as well as their consequences (such as immunologically mediated local and systemic disease). Our research models, discovery services, preclinical pharmacology models, safety assessment programs and full laboratory support services enable us to help your research in the field of bone and joint inflammatory diseases. 

Aginko can provide you infection and inflammation models to study a disease, a pharma or perfectionize your device.

Critical-size defects:
  • Calvaria critical-size defect in rats, rabbits
  • Mandibular critical-size defect in mini-pigs, in dogs
  • Femur critical-size defects in rats
  • Ulna critical-size defects in rabbits
  • Tibial critical-size defects in sheeps and mini-pigs
Osteotomy (fracture and segmental bone defects):
  • Tibial osteotomy in mini-pigs, in sheeps and goats
  • Mandibular osteotomy in sheeps
Outcome Measurements:
  • In vivo and ex-vivo BMD and BMC measurements of cortical and trabecula bones by DEXA, pQCT and microCT.
  • Biomechanical testing
  • Physiological bone turnover markers (blood, urine)
  • Ash chemical analysis
  • Histomorphometry, histology
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AGINKO Research AG, Route de l'ancienne Papeterie 7
1723 Marly , Switzerland