Aginko
Spine models

Validated small and large animal models are available to study spinal fusion at the cervical, thoracic and lumbar levels using anterior or posterior approaches.

Capture d’e?cran 2017-05-01 a? 19.54.44.png

 

CT scan view of dog PLF model 4 weeks post surgery (right bone volume calculation)

Species Available:

  • Rabbits
  • Rats
  • Dogs
  • Goats and sheep
  • Pigs
  • Primates

 C0003599_2016-11-10_16_35_40.jpg 5493-1.png

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

View of dog PLF model 12 weeks post surgery ( left :Micro CT, Right : Faxitron)

 

Types of Models:

 

Procedures are usually performed on one level but multilevel fusions are also possible:

 

  • Anterior cervical fusion
  • Anterior cervical discectomy (sheep, goats)
  • Posterolateral lumbar fusion (PLF) (rats, rabbits, dogs, sheep, pigs, primates)
  • Posterior thoracic fusion (rats)
  • Posterolateral interbody fusion (dogs, sheep)

 

Outcome Measures:

 

The fusion success can be assessed following established procedures:

 

  • Radiography: intervertebral angle
  • CT and Micro CT (fusion status and bone volume)
  • High Resolution X-Rays ( Faxitron)
  • Non invasive biomechanical testing
  • DXA: bone mineral density
  • Histology and histomorphometry: bone quality

Macintosh HD:Users:pommeboissier:Desktop:Capture d’e?cran 2017-05-30 a? 13.30.02.png

 

Macintosh HD:Users:pommeboissier:Desktop:Capture d’e?cran 2017-05-30 a? 13.30.02.png

Figure : PMMA histology on a dog PLF model (upper picture) and a rabbit PLF model.

To read more about Spine Models, Click Here 

Copyright © 2017 Allrights reserved
AGINKO Research AG
AGINKO Research AG, Route de l'ancienne Papeterie 7
1723 Marly , Switzerland